spark_auto_mapper_fhir.backbone_elements.substance_protein_subunit

Module Contents

Classes

SubstanceProteinSubunit

SubstanceProtein.Subunit
class spark_auto_mapper_fhir.backbone_elements.substance_protein_subunit.SubstanceProteinSubunit(*, id_=None, extension=None, modifierExtension=None, subunit=None, sequence=None, length=None, sequenceAttachment=None, nTerminalModificationId=None, nTerminalModification=None, cTerminalModificationId=None, cTerminalModification=None)

Bases: spark_auto_mapper_fhir.base_types.fhir_backbone_element_base.FhirBackboneElementBase

SubstanceProtein.Subunit

A SubstanceProtein is defined as a single unit of a linear amino acid sequence, or a combination of subunits that are either covalently linked or have a defined invariant stoichiometric relationship. This includes all synthetic, recombinant and purified SubstanceProteins of defined sequence, whether the use is therapeutic or prophylactic. This set of elements will be used to describe albumins, coagulation factors, cytokines, growth factors, peptide/SubstanceProtein hormones, enzymes, toxins, toxoids, recombinant vaccines, and immunomodulators.

A SubstanceProtein is defined as a single unit of a linear amino acid

sequence, or a combination of subunits that are either covalently linked or have a defined invariant stoichiometric relationship. This includes all synthetic, recombinant and purified SubstanceProteins of defined sequence, whether the use is therapeutic or prophylactic. This set of elements will be used to describe albumins, coagulation factors, cytokines, growth factors, peptide/SubstanceProtein hormones, enzymes, toxins, toxoids, recombinant vaccines, and immunomodulators.

param id_

None

param extension

May be used to represent additional information that is not part of the basic

definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

param modifierExtension

May be used to represent additional information that is not part of the basic

definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element’s descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

param subunit

Index of primary sequences of amino acids linked through peptide bonds in

order of decreasing length. Sequences of the same length will be ordered by molecular weight. Subunits that have identical sequences will be repeated and have sequential subscripts.

param sequence

The sequence information shall be provided enumerating the amino acids from N-

to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence.

param length

Length of linear sequences of amino acids contained in the subunit.

param sequenceAttachment

The sequence information shall be provided enumerating the amino acids from N-

to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence.

param nTerminalModificationId

Unique identifier for molecular fragment modification based on the ISO 11238

Substance ID.
param nTerminalModification

The name of the fragment modified at the N-terminal of the SubstanceProtein

shall be specified.
param cTerminalModificationId

Unique identifier for molecular fragment modification based on the ISO 11238

Substance ID.
param cTerminalModification

The modification at the C-terminal shall be specified.

Parameters